STUDIES ON ANTIBIOTIC SF-733, A NEW ANTIBIOTIC. II

Studies on a new pigment antibiotic, chrothiomycin.

Ghrothiomycin inhibits reactions of tyrosine hydroxylase1} and dopamine /?-hydroxylase2>3). It also exhibits weak antibacterial activities. It is obtained as blackish purple crystals containing sulfur and named chrothiomycin. In this paper, characters of chrothiomycin-producing Streptomyces are described together with the chemical and physical properties of the antibiotic and some of the biolog...

Studies on a new herbicidal antibiotic, homoalanosine.

Homoalanosine having a herbicidal activity was isolated from the culture filtrate of a soil isolate SC-1688 which was classified as Streptomyces galilaeus. The chemical structure of homoalanosine was determined to be L-2-amino-4-nitrosohydroxyaminobutyric acid by analyses of spectral and biological data. The antibiotic has high herbicidal activity at low concentrations against especially common...

Recent studies on albomycin, a new antibiotic.

A new antibiotic SF-2370 produced by Actinomadura.

Sir: A new indolocarbazole antibiotic SF-2370 has been found in the culture broth of Actinomadura sp. SF-2370 which was isolated from a soil sample collected at Shimizu, Shizuoka Prefecture, Japan. The antibiotic is weakly active against some bacteria and fungi. In this communication, the isolation, characterization, and structural elucidation by the spectral studies are reported. Actinomadura ...

Studies on a new polyether antibiotic, Ro 21-6150.

A new polyether antibiotic, Ro 21-6150, has been isolated from culture broths of Streptomyces hygroscopicus, strain X-14563. Ro 21-6150 has ionophore properties and is active in vitro against gram-positive bacteria.